maybe, you could remember the step, step by step, how to reach to the resolution, ( with the new profile) and then how many times you need to press left key, to reach a resolution like 800x600, all this using the keyboard, so, i recommend toput the laser of the mouse upside, with that way you could try using the keyboard and reaching to go there and change the resolution.
And outside there is a solution, but i dont remember too much, i think that you need to change some numbers ( that are of resolution) in the .exe file of the TDU, but i dont remember too much >.<
And there is another one ( that i found), is going to the .exe file of the TDU, then left click and then Proprieties, then upthere go to COmpatibility, and Tick one it says Run with a resolution of 640 x 480, then ( i think) you go inside the game and thengo to options and change the resolution to a lower one, after that, go to proprieties one more, and disactivate the Run with 640 x 480, and maybe will you with the resolution that you put inside ( the lower resolution one).
I dont anything more about that, just try those and good luck! ^^